U
UniProt
Data by UniProt Consortium
Search UniProtKB proteins, read curated function, localisation, disease, variant and drug-target annotation, and map gene, protein, Ensembl, ChEMBL, DrugBank, PDB and OMIM identifiers.
life-sciences, proteins, genes, uniprot, bioinformatics, drug-targets
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Tools (3)
- getProteinEntryGet a curated UniProtKB entry by accession: function, subcellular location, disease involvement (with OMIM IDs), natural variant summary, DrugBank drugs targeting the protein, and identifiers that chain into other sources (Ensembl gene = Open Targets target ID, NCBI Gene, HGNC, ChEMBL target, OMIM, PDB). Use searchProteins or mapIds first to get the accession from a gene symbol.Free
- searchProteinsSearch UniProtKB proteins by gene symbol, protein name or free text. Defaults to human, reviewed (Swiss-Prot) entries. Use the returned accessions with getProteinEntry for function, disease, variants, drugs and cross-references, or with mapIds to convert identifiers.Free
- mapIdsConvert biological identifiers through UniProt: gene symbol <-> UniProt accession <-> Ensembl gene/transcript/protein, NCBI Gene, HGNC, ChEMBL target, DrugBank, PDB, OMIM, RefSeq protein. Mappings between two non-UniProt namespaces (e.g. geneSymbol -> ensemblGene) go through UniProt accessions. Ensembl gene IDs are Open Targets target IDs; ChEMBL target IDs chain into ChEMBL; DrugBank -> uniprot lists a drug's protein targets.Free