getTargetProfile

Free

Target druggability and safety profile from Open Targets: tractability by modality (small molecule, antibody, PROTAC, other), known safety liabilities with affected tissues and sources, target class, UniProt ID, essentiality, loss-of-function constraint and high-quality chemical probes. Pass the symbol or uniprotId to chembl-mcp searchTargets to get the ChEMBL target ID for bioactivity data.

Try it

Open in playground

kirha tools run opentargets_getTargetProfile \
  --input '{
    "targetId": "ENSG00000146648"
  }'

Uses the key saved by kirha auth login.

targetIdstring, required
Ensembl gene ID from searchEntities, e.g. ENSG00000146648