OpenFDA

searchPurpleBook

Free

Search the FDA Purple Book of licensed biological products (BLAs): reference products, biosimilars and interchangeables, with licensure and interchangeability dates, reference product, and reference-product, first-interchangeable and orphan exclusivity expiries. Use referenceProduct to list every biosimilar of a biologic (e.g. adalimumab, Stelara). One row per BLA; applicationNumber (BLA761378) joins openfda-mcp searchDrugApprovals. Small-molecule drugs are in searchOrangeBook.

Try it

Open in playground
kirha tools run openfda_searchPurpleBook \
  --input '{}'

Uses the key saved by kirha auth login.

  • approvedAfterstring, YYYY-MM-DD

    YYYY-MM-DD

  • limitinteger, default 10, 1 to 50
  • newThisMonthboolean, default false

    Only BLAs newly approved in the latest monthly release

  • pathwaystring

    One of reference_product, biosimilar, interchangeable

  • querystring, default ""

    Proprietary name, proper name, applicant or BLA number, e.g. Humira, ustekinumab, Samsung Bioepis

  • referenceProductstring

    Reference product proper or proprietary name; returns its biosimilars/interchangeables, e.g. adalimumab, Stelara

  • sortBystring, default "relevance"

    One of relevance, approval_date_desc, approval_date_asc, interchangeable_approval_desc