OpenFDA

searchOrangeBook

Free

Search the FDA Orange Book (approved small-molecule drug products with therapeutic equivalence evaluations) by trade name, ingredient, applicant or patent number, and screen NDAs by when their last listed patent or exclusivity expires (loss-of-exclusivity screens). Returns one row per NDA/ANDA application with patent and exclusivity summary; use getOrangeBookPatents with an applicationNumber for the full patent, exclusivity and generic-entry detail. Biologics are not in the Orange Book: use searchPurpleBook.

Try it

Open in playground
kirha tools run openfda_searchOrangeBook \
  --input '{}'

Uses the key saved by kirha auth login.

  • applicationTypestring

    NDA = brand/505(b)(2), ANDA = generic

    One of NDA, ANDA

  • limitinteger, default 10, 1 to 50
  • marketingStatusstring

    One of rx, otc, discontinued

  • protectionEndsAfterstring, YYYY-MM-DD

    YYYY-MM-DD. Keep applications whose last patent/exclusivity expiry is on or after this date

  • protectionEndsBeforestring, YYYY-MM-DD

    YYYY-MM-DD

  • querystring, default ""

    Trade name, ingredient, applicant or patent number, e.g. Ozempic, apixaban, 8129343

  • referenceListedDrugOnlyboolean, default false
  • sortBystring, default "relevance"

    One of relevance, protection_end_asc, protection_end_desc, approval_date_desc, approval_date_asc